General Cell Lines and Cell Cultures
Amsbio LLC Human Esophageal cancer and normal adjacent tissue FFPE block
Human Esophageal cancer and normal adjacent tissue FFPE block
Promocell GmbH PromoCell NHEK-c 500,000 Human Epidermal Keratinocytes, single donor, adult, cryopreserved
Primary Normal Human Epidermal Keratinocytes (NHEK) are available from single or from pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells.Epidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.Keratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.
Amsbio LLC eLuCidate™ RAW 264.7, NFAT Reporter Cell Line
eLuCidate™ RAW 264.7 NFAT Reporter Cell Line
Abcam O x ytocin, Reproductive hormone, 5MG
MW 1007.2 Da, Purity >95%. Oxytocin, Reproductive hormone. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
ACROBiosystems HEK293/Human ErbB3 Stable Cell Line
ErbB3,also known as Her3 (human epidermal growth factor receptor 3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain. It therefore can bind the ligand but cannot mediate the intracellular signal transduction through protein phosphorylation. However, it does form heterodimers with ErbB2 or other EGFR members responsible for tyrosine phosphorylation to give a receptor complex and initiate the related pathway, which lead to cell proliferation or differentiation. Overexpression of this protein has been reported in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.
Lonza Walkersville ADSC - Suppl Growth Factors
Stem cells possess the unique ability to proliferate as an undifferentiated cell type then when properly stimulated differentiate into multiple lineages of cells Lonza s ADSC human Adipose Derived Stem Cell Growth BulletKit Medium is a serum containing medium designed to proliferate human adipose derived mesenchymal stem cells (both normal and diseased) in an undifferentiated state The serum used in Lonza s ADSC human Adipose Derived Stem Cell Growth BulletKit Medium is specifically screened to ensure that the serum neither promotes spontaneous differentiation of cells nor inhibits cell differentiation to osteogenic chondrogenic or adipogenic lineages (when properly stimulated with an appropriate differentiation media)
Biochain Institute Inc Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Colon, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
ABclonal Technology Dopamine Receptor D3 (DRD3) Rabbit pAb
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
ATCC SW948; Colon Adenocarcinoma; Human (Homo sapiens)
SW948 is a cell line exhibiting epithelial morphology from the colon of a White, 81-year-old, female patient with adenocarcinoma colorectal Dukes' type C, grade III. This cell line was deposited by A Leibovitz.
Biochain Institute Inc Matched Pair - Paraffin Tissue Section - Human Primary Tumor and Normal (PP): Colon, 5 x2 slides /PK
BioChain's FFPE human paraffin tissue (FFPE) section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of paraffin tissue sections of primary tumor and its adjacent normal tissue; PM consists of paraffin tissue sections of primary tumor and corresponding metastatic tumor. Paraffin tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor- specific genes and tumor metastatic genes.
ATCC Respiratory Inclusivity Panel
This panel of five quantitative genomic RNA and one quantitative, heat-inactivated preparation was selected from viral strains commonly cited in limit-of-detection studies or as control materials in SARS-CoV-2 EUA submissions and/or FDA 510(k) submissions.
Eurofins Discoverx PathHunter TACR1 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0717C3)
The PathHunter TACR1 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of TACR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged TACR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting TACR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter HCRTR1 Total GPCR Internalization U2OS Cell Line, 2 vials. (93-0729C3)
The PathHunter HCRTR1 Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of HCRTR1 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged HCRTR1 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the HCRTR1 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.